Antiphospholipid syndrome (APS) is an autoimmune disorder that causes an increased risk of blood clots. It occurs when the immune system mistakenly creates antibodies that attack phospholipid-binding proteins in the body, which makes the blood more likely to clot. APS can occur on its own, but it is often found in patients who have other autoimmune disorders, especially systemic lupus erythematosus (commonly known as "lupus") . Some people have general symptoms that can be similar to those of multiple sclerosis, such as tiredness or numbness and tingling in different parts of the body. The symptoms of APS can include blood clots, stroke, transient ischemic attack (TIA), rash, and others. APS can affect people of all ages, including children and babies. The risk factors for developing APS include being female, having other autoimmune disorders, and genetic, hormonal, and environmental factors. The treatment for APS aims to prevent clot-related events and may include blood thinners, aspirin, and corticosteroids. Women with APS who are pregnant may be advised to use heparin, low-dose aspirin, corticosteroids, or intravenous immunoglobulin during their pregnancies to help prevent a miscarriage.