There is no clear definition of "attrcm" in the search results. However, there is a medical condition called Transthyretin Amyloid Cardiomyopathy (ATTR-CM), which is a rare but severe cause of restrictive cardiomyopathy. ATTR-CM is caused by the accumulation of transthyretin, a protein, in the heart muscle, leading to thickening and stiffening of the heart, which can result in heart failure. Symptoms of ATTR-CM can vary or be subtle, and the condition is often misdiagnosed. In its early stages, it may mimic the symptoms of other conditions, such as heart failure related to high blood pressure, or hypertension, and enlargement and thickening of the heart, or hypertrophic cardiomyopathy. The disease is more common in localized parts of Portugal, Sweden, and Japan, and some variants are more common in people of Irish ancestry while others are common among people of African descent. There are two types of ATTR-CM: hereditary and wild-type. Hereditary ATTR-CM is caused by an inherited change (mutation) in the TTR gene, while wild-type ATTR-CM occurs for no known reason. Tafamidis is a drug used to treat ATTR-CM, which stabilizes the TTR protein and prevents it from breaking apart and forming fibrils.