Autosomal dominant is a pattern of inheritance characteristic of some genetic disorders. In this pattern, a single copy of the mutated gene from one parent is enough to cause the disorder. This means that if a parent has an autosomal dominant condition, there is a 50% chance that their child will inherit the condition. Autosomal dominant disorders have pedigrees that demonstrate a vertical pattern of inheritance).
Some key points about autosomal dominant inheritance include:
- The changed gene is a dominant gene located on one of the non-sex chromosomes, called autosomes.
- Only one parent needs to have an altered gene to pass it on to their child.
- Half of the children of a parent with an autosomal trait will get that trait.
- Autosomal dominant disorders can also occur as a new condition in a child when neither parent has the abnormal gene.
Examples of autosomal dominant disorders include Huntingtons disease, Marfan syndrome, and neurofibromatosis type 1.