Azelastine is a medication used to relieve nasal symptoms such as runny, itching, or stuffy nose, sneezing, and post-nasal drip caused by allergies or other conditions. It is an antihistamine that works by blocking certain natural substances called histamines that are responsible for nasal symptoms. Azelastine nasal spray is used to help relieve symptoms of seasonal or perennial allergic rhinitis (hay fever), vasomotor rhinitis, or other upper respiratory allergies. It is also used to relieve symptoms of nonallergic rhinitis such as sneezing and runny or stuffy nose which are not caused by allergies in adults and children 12 years of age or older. Azelastine nasal spray is usually sprayed in each nostril one or two times a day, and it is important to follow the directions on the prescription label carefully. It is designed to provide a certain number of sprays, and after the marked number of sprays has been used, the remaining sprays in the bottle might not contain the correct amount of medication. Therefore, it is important to keep track of the number of sprays used and throw away the bottle after the marked number of sprays has been used, even if it still contains some medication.