Bone cancer is a rare type of cancer that begins when cells in the bone start to grow out of control. It can harm normal bone tissue and destroy it. Bone cancer is different from cancers that begin elsewhere in the body and spread to the bone. The most common types of bone cancer include osteosarcoma, chondrosarcoma, and Ewing sarcoma. Symptoms of bone cancer include bone pain, swelling and tenderness near the affected area, weakened bone leading to fracture, fatigue, and unintended weight loss. Bone cancers are broken down into separate types based on the type of cell where the cancer began. The exact cause of bone cancer is not known, but certain factors are associated with an increased risk, including exposure to radiation or drugs during treatment for other cancers, and certain genetic conditions. Treatment for bone cancer usually involves surgical removal of the affected bone, chemotherapy, and radiation therapy. The decision to use surgery, chemotherapy, or radiation therapy is based on the type of bone cancer being treated. If you or your child are experiencing persistent, severe, or worsening bone pain, it is best to visit a doctor for further investigation.