DLSS (Deep Learning Super Sampling) sharpness is a setting that allows gamers to adjust the sharpness of the image produced by DLSS technology. DLSS is a technique that uses "temporal super-resolution" to improve the image quality of each frame, allowing gamers to enjoy the sharpest images possible without sacrificing framerate or performance. DLSS sharpness is a slider that can be adjusted to fine-tune the sharpness of the images or make them sharper overall.
According to a Reddit post, setting the DLSS sharpness below 50 can result in horrible blurriness in motion across multiple games, including Uncharted 4 and Spider-Man. The built-in DLSS sharpness setting can also cause an image shift/halo between a still camera and a camera thats panning. However, DLSS sharpness does not seem to have a significant effect on performance, although it may slightly improve or worsen depending on the game and settings.
In summary, DLSS sharpness is a setting that allows gamers to adjust the sharpness of the image produced by DLSS technology. It can be used to fine-tune the sharpness of the images or make them sharper overall. However, setting the DLSS sharpness below 50 can result in horrible blurriness in motion across multiple games.