EDS stands for Ehlers-Danlos syndromes, which are a group of 13 heritable connective tissue disorders caused by genetic changes that affect connective tissue. Connective tissue provides support in skin, tendons, ligaments, blood vessels, internal organs, and other structures in the body. Each type of EDS has its own set of features with distinct diagnostic criteria, but some features are seen across all types of EDS, including joint hypermobility, skin hyperextensibility, and tissue fragility. Joint hypermobility refers to the ability to extend joints further than is usual, while skin hyperextensibility means that the skin can stretch more than normal. Tissue fragility means that the body’s organs and other structures are more vulnerable to damage, which can present as easy bruising and poor wound healing in many types of EDS. Some types of EDS can also cause severe fragility of the skin, blood vessels, abdominal organs, eyes, gums, and bones. Symptoms of EDS can vary considerably from person to person, even in the same type of EDS and within the same family, but they commonly include long-term pain, chronic fatigue, dizziness, palpitations, and digestive disorders. There is no specific treatment for EDS, but its possible to manage many of the symptoms with support and advice from healthcare professionals such as physiotherapists and occupational therapists.