Enbrel (etanercept) is a type of medicine known as a biologic, which means its made from living cells. It is designed to attach to TNF proteins to help block their activity and reduce inflammation. Enbrel is used to treat several conditions, including:

• Moderately to severely active rheumatoid arthritis
• Psoriatic arthritis
• Ankylosing spondylitis
• Moderate to severe plaque psoriasis in adults and children 4 years and older
• Moderately to severely active polyarticular juvenile idiopathic arthritis in children ages 2 years and older

Enbrel works by reducing the signs and symptoms of these conditions, such as joint swelling, pain, fatigue, and stiffness. It can also help prevent joint damage caused by these conditions. However, Enbrel can lower the ability of your immune system to fight infections, and serious infections have happened in patients taking Enbrel. Therefore, it is important to talk to your doctor about your specific risk and any symptoms you may experience while taking Enbrel.