Goldenseal powder is made from the dried root of the goldenseal plant, which is a perennial herb in the buttercup family native to North America. Goldenseal contains several isoquinoline alkaloids, including berberine and hydrastine, which have been found to have antibacterial and antifungal effects. It is often used as a natural antibiotic and immune booster, and is sometimes combined with echinacea to treat or prevent upper respiratory infections, colds, and the flu. Goldenseal has also been used historically by Native Americans for a variety of conditions, including skin disorders, ulcers, and fevers. However, there is very little scientific evidence to support the use of goldenseal for any health-related purpose. Goldenseal powder is commonly sold as a dietary supplement and can be mixed into drinks or smoothies. It is important to note that goldenseal can interact with certain medications and may increase the risk of bleeding during surgery, so it is important to talk to a healthcare provider before using goldenseal powder.