The Griff Rule is a trend on TikTok that involves the creator asking a question and specifying that the viewer must respond with a particular answer. The questions are often light-hearted and playful, allowing users to engage with each other and showcase their creativity. The responses to these questions can be humorous, relatable, or simply entertaining. The trend has become a fun way for TikTok users to connect and engage with each other, fostering a sense of community on the platform. The term "Griff Rule" does not seem to have any other meaning or significance beyond this trend on TikTok.