Ketoconazole cream is an antifungal medication used to treat skin infections caused by a fungus or yeast. It can treat different types of fungal infections, including:

• Tinea corporis (ringworm)
• Tinea cruris (jock itch)
• Tinea pedis (athletes foot)
• Tinea versicolor (a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs)
• Seborrheic dermatitis (a condition that causes itchy, dry, and flaky skin)

Ketoconazole cream works by killing the fungus or yeast or preventing its growth. It is available in cream, gel, and shampoo forms, and can be purchased over-the-counter or with a prescription depending on the condition being treated. The cream is usually applied once or twice a day, and the shampoo is used once or twice a week. The most common side effects of the cream and shampoo are irritated or red skin.