Lipogenesis is a metabolic process that involves the synthesis of fatty acids from non-lipid precursors such as glucose, amino acids, and acetyl-CoA. It is the process of producing lipid or fat. The excess energy that will not be used immediately can be stored in the form of fats. Lipogenesis occurs mainly in the liver and adipose tissue, but it also occurs to some extent in other tissues such as the gut and kidney. The process of lipogenesis is stimulated by a high carbohydrate diet and insulin, which activates two enzymatic pathways, pyruvate dehydrogenase (PDH), and acetyl-CoA carboxylase (ACC) . Insulin also promotes glucose uptake by adipose tissue, which can occur through the use of glucose transporters directed to the plasma membrane or through the activation of lipogenic and glycolytic enzymes via covalent modification. Lipogenesis includes fatty acid synthesis and triglyceride synthesis, which occur in the cytoplasm and endoplasmic reticulum, respectively. The cells that carry out lipogenesis are mostly adipocytes and liver cells.