Methocarbamol is primarily used as a muscle relaxant to treat acute musculoskeletal conditions involving muscle pain, stiffness, and spasms. It works by calming overactive nerves and reducing nerve activity in the spinal cord, which helps relax muscles and relieve discomfort

. Common uses include:

• Relief of muscle pain and stiffness caused by strains, sprains, or injury

• Adjunct treatment alongside rest and physical therapy for skeletal muscle conditions

• Short-term relief of painful musculoskeletal conditions affecting muscles, bones, and joints

• Historically, it was used for tetanus muscle spasms, though benzodiazepines have largely replaced it for this purpose

Off-label uses may include:

• Non-specific low back pain (acute or chronic)
• Fibromyalgia
• Myofascial pain
• Inflammatory arthritis
• Rib fractures
• Postoperative care for hip or knee replacements
• Abdominal muscle cramps in cirrhosis patients

Methocarbamol is not effective for muscle spasticity from upper motor neuron disorders such as cerebral palsy

. In summary, methocarbamol is used to relax muscles and relieve pain and discomfort from acute musculoskeletal injuries and conditions, often combined with rest and physical therapy