Motor Neurone Disease (MND) is a rare and progressive condition that affects the nervous system, leading to muscle weakness and visible wasting. It is caused by the degeneration and premature death of motor neurons, which are specialist nerve cells in the brain and spinal cord that control muscle activity such as gripping, walking, speaking, swallowing, and breathing. MND is a group of diseases that includes amyotrophic lateral sclerosis (ALS), progressive muscular atrophy (PMA), progressive bulbar palsy (PBP), primary lateral sclerosis (PLS), and Kennedys disease, also known as spinal and bulbar muscular atrophy (SBMA). The symptoms of MND happen gradually and may not be obvious at first, but early symptoms can include weakness in the ankle or leg, slurred speech, and difficulty swallowing some foods. As MND progresses, it can become more difficult to do activities such as moving around, swallowing, and breathing. There is no cure for MND, but treatments such as riluzole, medicines to relieve muscle stiffness and help with saliva problems, and emotional support for the patient and their carer can help reduce the impact it has on a persons daily life. Multidisciplinary care can also help individuals be more comfortable while maintaining their quality of life.