MPa most commonly stands for megapascal, which is a metric unit of pressure or stress equal to one million pascals and often used to describe material strength or hydraulic pressure. MPA (or M.P.A.) also very commonly means Master of Public Administration, a graduate degree focused on leadership and management in government and nonprofit organizations. In medical contexts, MPA can refer to specific diseases or drugs (for example, microscopic polyangiitis), so the exact meaning depends on the field being discussed.