Neomycin and polymyxin b sulfates and dexamethasone ophthalmic ointment is a combination of a steroid and antibiotics used to treat eye infections and inflammation, including conjunctivitis and chronic anterior uveitis. It also prevents damage caused by chemicals, radiation, or foreign objects entering the eye. Neomycin and polymyxin B belong to the class of medicines known as antibiotics, which work by killing the bacteria or preventing their growth. Dexamethasone is a steroid medicine that is used to relieve the redness, itching, and swelling caused by eye infections. This medicine is available only with a doctors prescription. It is important to follow the directions on the prescription label and wash hands before and after use. Patients should be advised that their vision may be temporarily blurred following dosing with neomycin and polymyxin B sulfates and dexamethasone ophthalmic ointment, and care should be exercised in operating machinery or driving a motor vehicle.