what is novel drug delivery system

what is novel drug delivery system

1 year ago 41
Nature

A novel drug delivery system (NDDS) refers to the approaches, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effects. The conventional drug administration methods have many problems that may be potentially overcome by NDDS. The goal of NDDS is to improve drug potency, control drug release to give a sustained therapeutic effect, provide greater safety, and target a drug specifically to a desired tissue.

NDDS involves the formulation of new pharmaceutical forms that have optimized characteristics such as targeted delivery, slow delivery, and controlled rate of delivery. Colloidal drug carrier systems such as micellar solutions, vesicle and liquid crystal dispersions, as well as nanoparticle dispersions consisting of small particles show great promise as drug delivery systems.

NDDS typically involves nanotechnology-based approaches that require multidisciplinary efforts combining the fields of pharmaceutics, physical chemistry, polymer science, bioconjugate chemistry, and molecular biology. Targeted drug delivery approaches, such as passive targeting and active targeting, are also used in NDDS.

In summary, NDDS is a concept that involves the formulation of new pharmaceutical forms that have optimized characteristics to improve drug potency, control drug release, provide greater safety, and target a drug specifically to a desired tissue. It typically involves nanotechnology-based approaches and targeted drug delivery approaches.

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