Pain Hustlers is a 2023 film directed by David Yates, produced by Lawrence Grey, and starring Emily Blunt, Chris Evans, and a supporting cast that includes Catherine OHara, Jay Duplass, Brian dArcy James, and Chloe Coleman. The film takes place in the world of pharmaceuticals and follows Liza Drake, a high school dropout who lands a job with a failing pharmaceutical start-up in Central Florida. Liza is a single mother who dreams of a better life for her and her daughter, but she soon finds herself dealing with an increasingly unhinged boss, the worsening medical condition of her daughter, and a growing awareness of the devastation the company is causing. Pain Hustlers is a sharp and revealing look at what some people do out of desperation and others do out of greed. The film is a fictionalized account of the rise and fall of a pharmaceutical company that enjoyed a period of financial success on the backs of the opioid epidemic through a program that paid doctors lucrative "speaking fees" to encourage them to prescribe Subsys, a fentanyl-based pain medication, to their patients.