Proton pump inhibitors (PPIs) are a class of medication that work by reducing the amount of stomach acid made by glands in the lining of the stomach. They are used to treat conditions that are caused by either an overproduction of stomach acid or exacerbated by stomach acid, such as acid reflux, gastroesophageal reflux disease (GERD), and peptic ulcer disease. PPIs are available in both prescription and over-the-counter forms, and there are many names and brands of PPIs available, including omeprazole (Prilosec), esomeprazole (Nexium), lansoprazole (Prevacid), rabeprazole (AcipHex), pantoprazole (Protonix), dexlansoprazole (Dexilant), and Zegerid (omeprazole with sodium bicarbonate) .

PPIs are taken orally as tablets or capsules, and they are commonly taken 30 minutes before the first meal of the day. They are generally considered safe when taken at the recommended dosage for the recommended duration of time. However, they have been associated with several serious adverse effects, including an increased risk of bone fractures, kidney disease, and infections such as pneumonia and Clostridium difficile.

It is important to note that PPIs should only be taken under the guidance of a healthcare provider, and that overuse of PPIs can lead to potential risks and side effects. If you have a prescription for a PPI, the reasons for it should be reviewed periodically to make sure theyre still valid, and you should talk to your healthcare provider if you find you have to take these medicines on most days.