Radiesse is an injectable dermal filler used to fill specific areas of the face and hands, and it stimulates the bodys natural collagen, filling in wrinkles long term and helping to restore volume to the face. Unlike traditional dermal fillers that rely on hyaluronic acid, Radiesse features unique calcium-based microspheres to help restore facial volume and reverse signs of aging. It is the first and only FDA-approved CaHA portfolio that provides immediate contouring plus stimulation of collagen and elastin production. The microspheres are eventually absorbed by the body, leaving only natural collagen in place. Radiesse can provide a smooth, natural-looking result, whether its improvement in the lower face or the hands. It is often used to fill in wrinkled areas in the skin surrounding the nose and mouth, and some people choose this procedure to fill in wrinkled areas in their hands. Radiesse is considered an elective cosmetic procedure, and it is not likely that insurance will cover the injections.