According to Urban Dictionary, "red pilled" is a phrase that has become popular among cyberculture and signifies a free-thinking attitude, and a waking up from a "normal" life of sloth and ignorance. It is a metaphor representing the choice between a life of harsh knowledge and a life of comfortable ignorance. The term "red pill" comes from the movie "The Matrix," in which the main character, Neo, is offered a choice between taking a blue pill, which would allow him to remain in a simulated reality, or a red pill, which would awaken him to the true nature of his existence.

In more political terms, being "red pilled" likely means that someone is conservative and/or center-right winged, while being "blue pilled" means agreeing with and believing in mainstream liberal ideology.