Royal jelly is a milky secretion made by worker honeybees (Apis mellifera) . It is used to feed larvae in the honeycomb, and larvae that are to become queens are fed the royal jelly secretions in large amounts and until they are fully developed. Royal jelly is rich in carbs, protein, amino acids, fatty acids, vitamins, and minerals. Its composition varies depending on geography and climate. People use royal jelly for various purposes, including symptoms of menopause, hay fever, diabetes, premenstrual syndrome (PMS), obesity, dry eye, and many other purposes, but there is no good scientific evidence to support these uses. Royal jelly is sometimes included in topical skin care products to support maintenance of healthy, younger-looking skin. Animal research indicates that royal jelly may support increased collagen production and protection from skin damage associated with UV radiation exposure. However, human research on the anti-aging benefits of oral or topical royal jelly use is insufficient, and more studies are needed. Royal jelly is available in its natural state, powder, or capsule form, and benefits have been observed in a wide range of dosages. Royal jelly is possibly safe when used short-term, but it might cause skin irritation and rash in some people when applied to the skin. While using royal jelly is likely safe for most people, serious adverse reactions have occasionally been reported, including asthma, anaphylaxis, and contact dermatitis.