Stage 2 cancer refers to larger tumors or cancers that have grown more deeply into nearby tissue. In this stage, the cancer may have spread to the lymph nodes, but not to other parts of the body. Stage 2 cancers are more advanced than stage 1 cancers, and they are typically larger than stage 1 cancers and/or have spread to nearby lymph nodes. The stage of a cancer describes the size of a tumor and how far it has spread from where it originated, while the grade describes the appearance of the cancerous cells. In general, stage 2 cancers tend to be treated locally with surgery and/or radiation therapy. Chemotherapy or other drugs may be used during stage 2 cancer treatment in some cases. The treatment options for stage 2 cancer depend on the type of cancer and other factors, such as the patients overall health and medical history.