Tacrolimus ointment is used to treat the symptoms of eczema, specifically atopic dermatitis, in patients who cannot use other medications for their condition or whose eczema has not responded to another medication. Atopic dermatitis is a skin condition where there is itching, redness, and inflammation, much like an allergic reaction. Tacrolimus helps to suppress these symptoms which are reactions caused by the bodys immune system. It is a topical calcineurin inhibitor that works by stopping the immune system from producing substances that may cause eczema. It is applied twice a day to the affected area, and it should not be used on skin areas that have cuts or scrapes. It is important to note that a small number of patients who used tacrolimus ointment or another similar medication developed skin cancer or lymphoma (cancer in a part of the immune system). Therefore, it is important to talk to your doctor about the risks of using tacrolimus ointment.