According to the search results, the best antibiotic for cat bites is amoxicillin with clavulanate. This drug combination is the current recommendation for antibiotic treatment for cat bites. Amoxicillin and clavulanate is first-line therapy for the prophylactic treatment of dog, human, and cat bites. It is also indicated for high-risk infections. In addition, amoxicillin-clavulanate is the first-line prophylactic antibiotic for cat bites. It is important to note that antibiotic prophylaxis should be used for high-risk bite wounds and considered in average-risk wounds. Animal bite wound infections frequently are polymicrobial, and Pasteurella species are the most common pathogens found in cat bite wounds. Therefore, amoxicillin-clavulanate is the preferred choice because of the frequency of mixed infections.