The Centers for Disease Control and Prevention (CDC) is a United States federal agency under the Department of Health and Human Services. Headquartered in Atlanta, Georgia, the CDC's mission is to protect public health by preventing and controlling disease, injury, and disability in the U.S. and globally. It focuses on infectious diseases, foodborne pathogens, environmental health, occupational safety, health promotion, and injury prevention, among other areas. Originally founded in 1946 as the Communicable Disease Center to combat malaria, the CDC has expanded its scope over time to include chronic diseases, disabilities, workplace hazards, and bioterrorism preparedness. It serves as a major epidemiological center, conducting research, providing health information, and supporting public health programs. The CDC operates numerous specialized centers and offices focusing on different health areas and plays a key role in detecting and responding to emerging health threats like COVID-19, Ebola, and Zika virus. It also supports vaccination programs and promotes healthy behaviors and environments. Overall, the CDC is the nation's leading science-based, data-driven public health organization dedicated to protecting the health and safety of Americans and others worldwide through research, education, response, and prevention efforts. It is considered one of the foremost authorities on public health and disease control in the world. This summary reflects information current as of mid-2025.