The correct hand position for delivering effective chest compressions in CPR is to place the heel of one hand in the center of the chest, on the lower half of the breastbone (sternum). Then place the heel of the other hand directly on top of the first hand, interlocking or lifting the fingers so they do not touch the chest. The rescuer's shoulders should be positioned directly above the hands with arms straight and elbows locked to use body weight for compressions. Compressions should be delivered hard and deep, at least 2 inches (5 to 6 cm) deep, and at a rate of 100-120 compressions per minute. After each compression, allow the chest to fully recoil without lifting the hands off the chest.

It is also recommended that the dominant hand be placed on top of the non- dominant hand to help apply more pressure and achieve greater chest compression depth.