As of July 1, 2022, the population of Kansas City, Missouri is estimated to be 509,297. This makes it the largest city in Missouri by population and area. The city had a population of 508,090 as of the 2020 census. The population density of Kansas City is about 1,621 people per square mile. The largest racial/ethnic groups in Kansas City are White (55.5%), Black (26.3%), and Hispanic (10.7%) . The median age of Kansas City residents is 35.4 years.