In Texas Hold Em poker, the worst hand is generally considered to be 2-7 offsuit. This is because there are very few good options available with this hand, and it is impossible to make a straight or flush with both cards. Even if you end up with a pair of 7s or a pair of 2s, it is unlikely to be the best hand. Other hands that are considered to be among the worst include 2-8 offsuit, 3-8 offsuit, 2-9 offsuit, and 2-6 offsuit. It is generally recommended to fold these hands if you are dealt them, as there are almost no circumstances in which you should play them.