Selena Gomez has lupus, an autoimmune condition that causes chronic inflammation in many parts of the body, like the skin, joints, heart, kidneys, lungs, and even more. Lupus can cause a host of complications, including chronic pain, extreme fatigue, frequent fevers, skin rashes, kidney damage, heart problems, and even mental health problems like depression. Selena has been open about her condition and how it affects her physically and emotionally. She has undergone chemotherapy to treat her autoimmune disease. In addition to chemotherapy, she has also undergone a kidney transplant in 2017. Selena has been vocal about the other ways treatment has affected her body too. For example, she tends to hold a lot of water weight when she’s taking a certain medication. She has also experienced shaking due to her medication for lupus. In her documentary "My Mind & Me," Selena breaks down crying from the pain shes in due to her worsening lupus, which causes painful and weakening muscles. She has also been diagnosed with bipolar disorder. Selena has been to rehab in the past for her mental health and has been open about how therapy has changed her life.