To mine Mythril in Terraria, you need a pickaxe with a power of 110 or higher. The following pickaxes can mine Mythril:

• Cobalt Pickaxe
• Palladium Pickaxe
• Mythril Pickaxe
• Orichalcum Pickaxe
• Adamantite Pickaxe
• Titanium Pickaxe

The Mythril Pickaxe is one of the pickaxes that can mine Mythril. It requires 15 Mythril Bars to craft (60 Mythril Ore) and has a power of 110.

Its worth noting that Mythril bars can also be purchased from the Goblin Tinkerer and the Mechanic for a fee, saving players the time and effort of mining or exploring for the material.