Indiana has the most Powerball jackpot winners in the history of the game, with 39 jackpot wins since 1992 when Powerball got its start. The other states with the most Powerball jackpot winners are Missouri with 31 wins, Minnesota with 22 wins, Pennsylvania and Wisconsin with 19 wins each, and Kentucky with 18 wins. Its important to note that not all states that play Powerball have had a jackpot winner, and some states have only had one Powerball jackpot since 2003. Additionally, five states dont have state lotteries: Alabama, Alaska, Hawaii, Nevada, and Utah.