There are four sexually transmitted infections (STIs) that are not curable: herpes (HSV), hepatitis B (HBV), human immunodeficiency virus (HIV), and human papillomavirus (HPV) . Although these infections cannot be cured, they can be managed with treatment and medication. It is important to receive treatment for these diseases as soon as possible because early diagnosis and treatment have been shown to decrease long-term negative health consequences. Other STIs, such as chlamydia, gonorrhea, syphilis, and trichomoniasis, are generally curable with existing single-dose regimens of antibiotics). It is important to practice safe sex to prevent the spread of STIs, including properly and consistently using a condom, dental dam, or another form of protection every time you have sex.