The acceptable temperature range for a urine specimen is between 90°F to 100°F (32°C to 38°C) . The temperature of the urine specimen should be measured immediately after the donor provides the urine specimen to the collector, and the time from urination to temperature measurement may not exceed 4 minutes. The temperature-measuring device used must accurately reflect the temperature of the specimen and not contaminate the specimen. If the temperature of a urine specimen is outside the acceptable range, that is a reason to believe the donor may have altered (e.g., adulterated or diluted) or substituted the specimen. It is important to note that the temperature of a urine specimen can vary depending on the individuals health, the time of day, and other factors.