It seems that the phrase "what the fuck is this meme" is used in different contexts and does not refer to a specific meme. Here are some possible interpretations of the phrase based on the search results:

• In a Reddit post from r/tf2shitposterclub, the phrase is used to describe a meme that has no punchline or humor, and is only funny because it is a meme.
• In an Instagram post, the phrase is used to express surprise or disbelief about a clip that was posted earlier.
• In a Know Your Meme article, the phrase is part of a memorable line said by Joe Pescis character in an episode of Tales from the Crypt upon looking at an unusually designed mansion. The clip of Joe Pesci saying the line gained virality as an exploitable meme format in which it was edited into various scenes and videos.
• In a GIPHY page, the phrase is used to search for GIFs that express confusion, shock, or disbelief.

Therefore, "what the fuck is this meme" can be interpreted as a phrase that expresses different emotions depending on the context in which it is used.