Restless leg syndrome (RLS) is a neurological disorder that causes unpleasant or uncomfortable sensations in the legs and an irresistible urge to move them. The exact cause of RLS is still unknown, but researchers suspect that it may be caused by an imbalance of the brain chemical dopamine, which sends messages to control muscle movement. Some cases of RLS are believed to be inherited, and specific gene variants have been associated with the condition. However, there are also several triggers that can make RLS symptoms worse, including:

• Alcohol
• Caffeine
• Nicotine
• Certain medications
• Stress
• Being overweight or obese
• Sitting or resting for prolonged periods

Certain medications can also aggravate RLS symptoms, such as some anti-nausea drugs, antipsychotic drugs, antidepressants that increase serotonin, and cold and allergy medications that contain older antihistamines. Additionally, some medical conditions can happen in addition to RLS, including iron deficiency anemia, chronic kidney disease, diabetes, Parkinsons disease, rheumatoid arthritis, an underactive thyroid, or fibromyalgia.

There is no known way to prevent RLS, but treatment is available. Simple self-care steps and lifestyle changes may help relieve symptoms, and medications also help many people with RLS. If you are experiencing symptoms of RLS, it is recommended to consult with a healthcare provider for proper diagnosis and treatment.