High cholesterol levels can increase the risk of heart attack and stroke. While medication and lifestyle changes are the primary ways to manage high cholesterol, some vitamins and supplements may also help lower cholesterol levels. Here are some vitamins and supplements that may help lower cholesterol:

1. Niacin: Niacin is a B vitamin that can help lower LDL cholesterol levels and triglycerides. However, it is important to speak with a doctor before taking niacin as it can cause side effects.

2. Omega-3 polyunsaturated fatty acids: Omega-3 PUFAs, also known as omega-3 fish oils or omega-3 fatty acids, can help lower triglycerides and LDL cholesterol levels. They are present in foods such as oily fish, seeds, and nuts, and supplements are also available.

3. Flaxseed: Flaxseed contains α-linolenic acid, lignans, and phenolic compounds, which can lower LDL and triglycerides in the blood. The dietary supplement form of flaxseed is usually an oil.

4. Garlic: Garlic supplements may slightly lower total and LDL cholesterol levels, but the evidence is not conclusive.

5. Red yeast rice: Red yeast rice supplements have been shown to lower cholesterol because they contain monacolin K, which has the same chemical makeup as lovastatin, a cholesterol-lowering medicine. However, it is important to note that monacolin K is not present in the red yeast rice sold in America.

6. Psyllium: Psyllium is a type of fiber that can help lower total cholesterol and LDL cholesterol levels. It is available in supplement form, but it is important to increase water intake when taking psyllium to avoid constipation.

7. Soy protein: Soy protein supplements can lower total and LDL cholesterol levels a little. Eating soy protein instead of animal protein can also help lower cholesterol levels.

8. Vitamin C: Vitamin C is an antioxidant vitamin that may reduce LDL oxidation, which is a key step in the development of atherosclerosis. This benefit may be especially notable in people with vitamin C deficiency.

9. Vitamin D: According to a 2021 review, vitamin D supplements may lower total and LDL cholesterol and triglycerides. They may also block foam cell formation and, as a result, the risk of atherosclerosis. The review also notes that vitamin D deficiency is associated with higher LDL levels.

It is important to note that while these vitamins and supplements may help lower cholesterol levels, they should not be used as a substitute for medical treatment. It is important to speak with a doctor before taking any supplements, as some may interact with medications or cause side effects.