People born on June 21 share the zodiac sign of Cancer). Cancer is the fourth sign of the zodiac, and it runs from June 21 to July 22). Cancer is a cardinal water sign represented by the crab). Those born under this sign are known for their compassion, empathy, and emotional depth. They tend to feel things deeply and have a knack for comforting those in need. Cancers are also known for their creativity and artistic abilities.