The regular Big Brother UK 2025 series (Big Brother 22) is set to start on Sunday, 28th September 2025, and will run for seven weeks until Friday, 14th November 2025. The show will air on ITV2 and ITVX and will be hosted by AJ Odudu and Will Best. This series will be the longest on ITV to date.

For additional context, Celebrity Big Brother 2025 started earlier on Monday, 7th April 2025, and ran for 19 days on ITV1.