The NFL Week 1 of the 2025 season will begin on Thursday, September 4, 2025. The season opener is set with the Dallas Cowboys facing the Philadelphia Eagles at Lincoln Financial Field in Philadelphia at 8:20 p.m. ET. The games for Week 1 will span from September 4 through September 8, 2025, including an international game on September 5 between the Los Angeles Chargers and Kansas City Chiefs in São Paulo, Brazil, and Monday Night Football on September 8 featuring the Minnesota Vikings at the Chicago Bears.