Cane toads (Rhinella marina) are originally from South and mainland Central America. Their native range extends from the Rio Grande Valley in South Texas down through Central America to parts of northern South America, including the Amazon basin and areas near Venezuela. They inhabit tropical and some semiarid environments in this region.

The cane toad is a large terrestrial toad native to these American regions, but it has been introduced to many other parts of the world, including Australia, various Pacific islands, the Caribbean, and parts of the southern United States, mainly to control agricultural pests.

In summary, cane toads are originally from tropical and seasonally dry areas of North, Central, and South America.