The Big Bend in Florida is an informal geographic region located in North Florida where the Florida Panhandle transitions into the Florida Peninsula, south and east of Tallahassee. It is situated along the northern end of Apalachee Bay and stretches eastward from the Forgotten Coast past the delta of the Suwannee River. The Big Bend region includes coastal counties such as Wakulla, Jefferson, Taylor, Dixie, and Levy, and extends inland with woodlands and marshes around rivers draining into the Gulf of Mexico

. The Big Bend Coast, part of this region, is a marshy coastline along the Gulf of Mexico extending about 350 kilometers (220 miles) from the western end of Apalachee Bay down to Anclote Key near the Tampa Bay area. This coast is characterized by salt marshes, mangrove forests, seagrass meadows, and oyster reefs, with no barrier islands between the Ocklockonee River and Anclote Key

. Key towns in the Big Bend region include Tallahassee (the principal city), Apalachicola, St. Marks, Carrabelle, Perry, Steinhatchee, and Cedar Key. The area is known for its natural features such as the largest single spring in the U.S., the Alapaha Rise, and the extensive Wakulla-Leon Sinks underwater cave system

. In summary, the Big Bend in Florida is the coastal and adjacent inland area where the Panhandle curves into the Peninsula, primarily along the Gulf Coast from Apalachee Bay eastward and southward toward the Tampa Bay region.