The closest U.S. state to Africa is Maine, specifically the easternmost point at Quoddy Head. The distance to the northwest African coast (around Morocco) is about 3,150 to 3,200 miles, depending on the exact measure used. Maine holds this distinction because its eastern edge sticks farther out toward the Atlantic than any other U.S. state, making it the nearest point in the continental United States to Africa. [web results indicate Quoddy Head in Maine as the closest point]

If you’d like, I can pull more precise distance figures from multiple sources or show a quick comparison with other near-coastal states like Massachusetts, New Hampshire, Connecticut, Rhode Island, and New York to illustrate how Maine compares.