Several characters from anime and comics are considered capable of beating Saitama, despite his overwhelming strength in "One Punch Man." These characters often possess abilities that go beyond mere physical power, including reality manipulation, immortality, or cosmic-level strength.

Anime Characters Who Can Beat Saitama

• Anos Voldigoad : A demon lord with feats like lifting attacks weighing the mass of a universe and destroying vast realms. His power to destroy planets, solar systems, and multiverses in a single blow likely surpasses Saitama's

• Rimuru Tempest : Known for creating and destroying thousands of universes and surviving universe-level blasts. Rimuru’s ability to stop time and regenerate makes him a formidable opponent against Saitama

• Zeno (Dragon Ball Super) : A godlike entity who can erase entire universes effortlessly, placing him above conventional fighters like Saitama

• Saiki Kusuo, Gojo Satoru, Naruto Uzumaki : Characters with powerful supernatural or magical abilities that could counter Saitama’s physical dominance

• Yugi Muto : While not stronger physically, Yugi can outsmart Saitama using the rules of card games and strategic thinking enhanced by the Millennium Puzzle

Comic Book Characters Who Could Defeat Saitama

• Superman : Particularly versions from the Silver Age, who can move planets and survive extreme conditions. Superman’s speed (faster than light) and strength could overwhelm Saitama, and he would only be vulnerable if Saitama used Kryptonite

• Thanos : An immortal Marvel villain who can absorb cosmic energy and manipulate matter. His durability and power, especially when wielding the Infinity Stones, make him capable of withstanding Saitama’s punches

• The Flash : His ability to move faster than light and manipulate time could allow him to defeat Saitama by turning back time or outpacing him

• Hulk, Thor, Darkseid : Other powerful characters from comics cited as potential challengers due to their immense strength and abilities

Summary

While Saitama is virtually unbeatable in physical combat within his own series, characters with reality-warping powers, godlike status, or cosmic- level strength from other anime or comic universes are theorized to be able to defeat him. These include Anos Voldigoad, Rimuru Tempest, Zeno, Superman, Thanos, and The Flash, among others

. Thus, the answer depends on the context and universe rules, but many powerful beings exist who could potentially beat Saitama.