Emma Raducanu beat the following players to win the 2021 US Open women's singles title:

• Stefanie Vögele
• Zhang Shuai
• Sara Sorribes Tormo
• Shelby Rogers
• Belinda Bencic
• Maria Sakkari
• Leylah Fernandez in the final

She won the final against Leylah Fernandez in straight sets, 6-4, 6-3. Raducanu made history by winning the US Open as a qualifier without dropping a set throughout the tournament, becoming the first qualifier ever to win a Grand Slam in the Open Era