For the 2025 football season so far, Ole Miss (the Rebels) has one loss and finished the regular season 11–1, with the only defeat coming against the Georgia Bulldogs in a road game on October 18, 2025.

If you meant Ole Miss men’s basketball instead, the Rebels’ first loss of the 2025–26 season was to the Iowa Hawkeyes by a score of 74–69 on November 25, 2025.