The Monday Night Football games on September 15, 2025, feature two matchups:
- Tampa Bay Buccaneers vs. Houston Texans at 7:00 PM ET, broadcast on ABC and ESPN.
- Los Angeles Chargers vs. Las Vegas Raiders at 10:00 PM ET, broadcast on ESPN.
The Texans host the Buccaneers at NRG Stadium in Houston, while the Chargers visit the Raiders at Allegiant Stadium in Las Vegas. This is a doubleheader event for Monday Night Football, with each game in its own time slot.
