On Monday night, September 16, 2025, the NFL Monday Night Football schedule features two games as part of a doubleheader. The matchups are:

• Houston Texans vs. Tampa Bay Buccaneers at 7:00 PM ET, broadcast on ABC and ESPN.
• Las Vegas Raiders vs. Los Angeles Chargers at 10:00 PM ET, broadcast on ESPN.

The Texans will host the Buccaneers at NRG Stadium in Houston, followed by the Chargers visiting the Raiders at Allegiant Stadium in Las Vegas. Both games will be available for streaming on Fubo as well. This doubleheader showcases competitive teams, with the Chargers and Raiders each starting the season strong in the AFC West division.