If you’re asking “who should I start in Week 10,” the best approach is to balance floor with upside based on your roster and the Week 10 matchups. Here’s a practical guide to help you lock in your lineup. Direct starts of the week (general guidance)

• Must-starts at RB: If you have a workhorse back who faces a weak run defense or a top-tier RB in a high-volume offense, lean into them. Look for players with projected volume and goal-line carries.
• Must-starts at WR: Target receivers with reliable targets and favorable matchups, especially in games expected to be high-scoring. PPR formats reward players who see a lot of short-area targets.
• Flex choices: Prioritize players with clear path to 8–15 touches or 5–8 targets, plus a ceiling for a TD. In Week 10, streaming WR3s or RB3s with favorable helpers (injury news or increased roles) can be valuable.

Strategy by position

• Quarterback: Start the safest option with a solid floor if you’re in need of reliability. If you’re chasing a ceiling play, consider a QB with a favorable matchup and recent scoring momentum.
• Running back: If you have a starting back who is the primary option and involved in the passing game, that’s usually a strong start. If you’re deciding between two backs, favor the one with more receptions/week and a matchup against a weak rush defense.
• Wide receiver: Prefer receivers who saw 8+ targets last week or who have a favorable matchup (opponent’s secondary weaknesses or high-paced offenses). Weather and opponent game plan can influence output, so account for those.
• Tight end: In Week 10, look for TEs with consistent target shares and red-zone involvement. If a top target is hurt or limited, a favorable matchup TE on the streamer radar can be a differentiator.

Waiver or deeper-ply options to consider before finalizing

• If you’re on the bubble, look for players who have earned an increased role due to injury or inefficiency in the starting lineup. A hot hand or a favorable upcoming schedule can turn a bench stash into a week-winning addition.
• If your lineup has a bye week or injuries, consider streamers who have favorable offenses and solid targets in the game plan for Week 10.

How to finalize your decision

• Check latest injury reports, practice participation, and any late-week weather impacts for Week 10 games.
• Compare projections from reliable sources focused on Week 10, then cross-check with your league’s scoring format (PPR vs standard) and roster needs.
• If you have a clear upgrade on your bench for a start in Week 10, prioritize that move even if it requires flexibility in other positions.

If you’d like, share:

• Your full Week 10 roster (positions and players you’re considering starting or sitting)
• Your league format (PPR, half-PPR, standard) and any notable scoring rules
• Any injury or matchup concerns you’re unsure about

With that, I can give you a precise, start/sit recommendation for each position for Week 10.