Molly Qerim left ESPN's First Take primarily due to contract negotiations that did not lead to an agreement. ESPN did not want to lose her, but Molly ultimately made the decision to step away from the show effective immediately. She expressed that the departure news came sooner than planned and not in the way she had hoped, highlighting her gratitude for her time on the show and the relationships formed. Stephen A. Smith, her co-host, confirmed the sudden nature of her resignation and mentioned that the specifics are private, emphasizing their long partnership and that Molly's decision was respected. ESPN also acknowledged her significant contributions over the years.

Additionally, Molly mentioned personal reasons like focusing on sobriety, mental health, and co-parenting as part of her current priorities, which also influenced her decision.